Programme

 

 

Thursday, June 6

13:00 – 17:00 YIN (Young investigators network)

13.00-13.05    welcome from the organizing committee

13.05-13.15    welcome from the YIN

 

13.15-14.00    Keynote lecture: Thierry van den Bosch

                          Eyes on the Map: Exploring Spatial Transcriptomics

14.00-14.30    YIN business

 

14.30-1500     Coffee

 

15.00-17.00    Basic research presentations

15.00                 Ruba Kal Omar

                           A Prognostic Score for the Prediction of Local Treatment Failure in Plaque Brachytherapy of Uveal Melanoma

15.10                 Laura Hoffmann

                           Experiences with an artificial intelligence-based assistant to distinguish choroidal nevi from uveal melanoma

15.20                 Erwin Brosens

                           Uveal Melanoma zebrafish xenograft models illustrate mutation status dependent effects of compound synergism or – antagonism

15.30                 Adriana Amaro

                           Molecular evidence for blue light as an etiological factor for uveal melanoma

15.40                 Quincy van den Bosch

                           Transcription regulators FOXD1 and RBFOX2 contribute to metastatic capacity in high-risk Uveal Melanoma

15.50                 Rui Wang

                           MiR-181a-driven downregulation of cholesterol biosynthesis through the inhibition of SREBP2 suppresses UM metastasis

16.00                 Mike Wu

                           Clinical applicability of methylated cell-free DNA (cfDNA) in uveal melanoma (UM) using methylated DNA sequencing (MeD-seq)

16.10                 Monica Maria Pagliara

                           Impact on metastatic risk of tumor microenvironment biomarkers and chromosomal aberrations in uveal melanoma

16.20                 Firas Kreidieh

                           Tumor infiltrating lymphocyte harvest and ex vivo expansion from primary and metastatic uveal melanoma tumors

16.30                 Anna Hagström

                           Melatonin receptor expression in primary uveal melanoma

16.40                 Natasha van Poppelen

                            The effect of proton beam therapy on cell metabolism of Müller cells and organoids derived from uveal melanoma cells

16.50                 Stine Dahl Vest

                           The genetic profile of large B-cell lymphomas presenting in the ocular adnexa

 

17.30-20.00     Welcome reception at Haga Bottega

 

 

Friday, June 7

09:00 – 09:30  New approaches for proton beam therapy planning

                          Jan-Willem Beenakker & Martin Janson

09:30 – 10:30  Uveal melanoma presentations

09.30                 Bertil Damato

                           Risk of metastatic death from small choroidal melanomas if treatment is deferred until tumor growth is detected: a study using LUMPO

09.40                 Gustav Stålhammar

                           Choroidal Nevi and Melanoma Doubling Times and Implications for Delays in Treatment: A Systematic Review and Meta-analysis

09.50                 Suzanne Phillips

                           A phase Ib study of endogenous T cell therapy using SLC45A2-specific CD8 memory T cells for patients with metastatic uveal melanoma

10.00                 Paweł Rogala

                           Retrospective Analysis of Tebentafusp Treatment in Metastatic Uveal Melanoma: One Center Study

10.10                 Roderick O’Day

                           Darovasertib for localized Ocular Melanoma

10.20                 Giulia Midena

                           Aqueous humor proteomic findings at diagnosis correlate with subsequent metastases of uveal melanoma

 

10.30-11.00    Coffee

 

11:00 – 11:30  Keynote lecture: Bita Esmaeli

                          Immunotherapy and targeted therapy for locally advanced or metastatic ocular adnexal cancers

 

11:30 – 13:00 Lunch

 

13:00 – 13:30  OOG Collaborative Initiatives, discussions about (future) joint projects

13:30-14:00    Keynote lecture: Bertil Damato

                          My forty years in ocular oncology – a case report

14:00 – 15:00 Uveal melanoma presentations continued

14.00                 Joni Turunen

                            Genetic predisposition to uveal melanoma in Finland

14.10                 Alexandre Matet

                            Identification of the monoallelic MBD4-associated neoplasia syndrome in uveal melanoma: from exceptional responders to familial predisposition

14.20                 Mari Mansikkamäki

                            Brachytherapy for juxtapapillary choroidal melanoma: comparison of slotted iodine and slotted ruthenium plaque radiotherapy

14.30                 Alessia Pica

                           Clinical outcomes in AYAs (adolescent and young adults) treated with proton therapy for uveal melanoma: a comparative matching study with elder adults

14.40                 Paul Foerster

                            First experience with self-shielding gyroscopic radiosurgery for uveal melanoma

14.50                 Jens Heufelder

                            Milestones and patient statistics of 25 years ocular proton therapy in Berlin

 

15.00-15.30    Coffee

 

15:30 – 17:00 Uveal melanoma presentations continued

15.30                 Emine Kilic

                           Dosimetric patterns for Toxicity-specific Profiles in Uveal Melanoma following Stereotactic Radiotherapy

15.40                 Ekaterina Sokolenko

                           Radiation Shielding for Ocular Brachytherapy

15.50                 Iwona Rospond-Kubiak

                           Orbital MRI vs ophthalmic ultrasound for the evaluation of intraocular tumors in eyes with opaque optic media

16.00                 Corné Haasjes

                           Optical aberration correction in fundus photographs for ocular proton therapy planning

16.10                 Tero Kivelä

                            Presumed incipient choroidal melanomas: an update

16.20                 Guy Missotten

                           Growing juxtapapillary tumors: melanocytoma or melanoma

16.30                 Emilia Zwolinska

                           Malignant transformation of low-risk choroidal nevi – a case series

16.40                 Michał Dopierała

                            Diagnostic Biopsy for Indeterminate Choroidal Melanocytic Lesions: A Case Series

16.50                 Susan Kennedy

                            Clinico-Pathologic and Molecular Analysis of enucleated Small (T1) Uveal Melanomas

17.00                 Vincenzina Mazzeo

                            Multiple tumors in uveal melanoma patients

 

18:30 – 22:00    Dinner, Vasa Museum

 

 

Saturday, June 8

09:00 – 10:00  OOG business meeting

10:00 – 10:30  Keynote lecture, Doris Hadjistilianou

                          Cancer in Greek mythology: The retinoblastoma paradigm

 

10:30 – 11:00  Coffee

 

11.00-12.00    Retinoblastoma presentations

11.00                 Nathalie Cassoux

                           Diffuse infiltrating retinoblastoma with anterior chamber involvement: conservative management and identification of RB1 alterations in aqueous humor

11.10                 Su-Chan Lee

                            BCOR loss promotes retinoblastoma growth by induction of IGF1 expression and activation of IGF1 receptor signaling

11.20                 Adeline Berger

                           Spatial transcriptomics in a poorly differentiated retinoblastoma with a retinocytoma area: a case study

11.30                 Paulina Bartoszek

                            Late intraocular recurrence of retinoblastoma in a teenager

11.40                 Vicktoria (Vicky) Vishnevskia-Dai

                            Orbital Development in Children with Retinoblastoma: An Imaging-Based Study

11.50                 Min Kim

                           The Spectrum of Vitreoretinal Diseases and Benign intraocular Tumors often misdiagnosed as intraocular malignancies

12.00-12.30     Delcath Symposium

 

12:30 – 13:30 Lunch

 

13:30 – 14:30  Rapid fire session (5+1 min. presentations)

13.30                 Gustav Stålhammar

                            Tailoring Metastatic Surveillance in Uveal Melanoma Based on Individual Metastatic Risk

13.36                 Hilary Reeves

                            True frequency of HLA-A*02:01 expression in metastatic uveal melanoma patients

13.42                 Viktor Gill

                            Incidence, Risk Factors and Outcomes of Cataract Surgery after Plaque Brachytherapy for Posterior Uveal Melanoma

13.48                 Shiva Sabazade

                            Deep Learning for Distinguishing Small Choroidal Melanomas from Nevi in Fundus Photographs: Development and Validation of an Accurate Algorithm

13.54                 Rumana Hussain

                            The Ocular oncology biobank and the development of a trusted research environment

14.00                 Alexandra Steinemann

                            Presentation of three Patients with Finding of Undifferentiated Carcinoma

14.06                 Arnaud Martel

                           Post-radiation management of scleral necrosis with deep temporal aponeurosis and vascularized conjunctival flap

14.12                 Luise Grajewski

                           The Risk of Recurrence of Conjunctival Melanoma after Excision and Adjuvant Brachytherapy with Ruthenium-106

14.18                 Anna Wiktorin

                           Cryosurgery of eyelid actinic keratosis and basal cell carcinoma – temperature mapping using IR technology

14.24                 Gustavo Savino

                           Breast cancer orbital metastases: clinical, imaging and histopathological features in a retrospective case series

 

14.30-15.00    Coffee

 

15:00 – 17:00  Periocular and orbital tumors presentations

15.00                 Heinrich Heimann

                            Proton beam radiotherapy for advanced ocular surface malignancies

15.10                 Raffaele Parrozzani

                           Subthreshold Micropulse Laser as a Novel Treatment of Radiation Macular Edema
                           Radiation Shielding for Ocular Brachytherapy

15.20                 Edoardo Midena

                            Adjuvant Iodine-125 Brachytherapy in Conjunctival Melanoma

15.30                 Jan-Willem Beenakker

                            MR-Imaging characteristics of intra-ocular tumours

15.40                 Guy Negretti

                           Intravitreal Bevacizumab for The Treatment of Choroidal Haemangiomas

16.00                Dr. Irem Koç

                            Yolk Sac Tumor of the Eye and Orbit: Diagnosis and management of Four Patients

16.10                 Li Teng Kok

                            Eyelid merkel cell carcinoma: Management and outcomes in a tertiary eye centre

16.20                 Denis Malaise

                            Choroidal MALT lymphoma: various clinical presentations of a rare disease

16.30                 Steffen Heegaard

                            Ocular adnexal T-cell lymphomas

16.40                 Maya Eiger-Moscovich

                            Seasonal variation in vitreoretinal lymphoma diagnosis

16.50                 Robert Verdijk
                           Evidence of MAPK pathway activation across subtypes of adult orbital xanthogranulomas irrespective of the presence of oncogenic mutations

 

19:00 – 22:00    Dinner. Nobel Price Museum

 

Sunday, June 9

 

10:00 – 12:00   Guided tour, St. Erik Eye Hospital